ISSN 0371-0874, CN 31-1352/Q



谢宇1,2,3, 王军朋1,3,*

1河南大学淮河医院转化医学中心,开封 475000;2河南大学体育学院,开封 475000;3河南大学感染与免疫研究所,开封 475000



关键词: 有氧运动; 免疫系统; 自身免疫病; 炎症


Advance in effect of aerobic exercise on immune system and autoimmune diseases

XIE Yu1,2,3, WANG Jun-Peng1,3,*

1Translational Medical Center of Huaihe Hospital, Henan University, Kaifeng 475000, China;2College of Physical Education, Henan University, Kaifeng 475000, China;3Institute of Infection and Immunity, Henan University, Kaifeng 475000, China


Autoimmune diseases are a kind of chronic diseases with unclear etiology, which has the characteristics of repetition and difficulty to cure completely. Aerobic exercise, as an effective intervention method for chronic diseases, has also received extensive attention in the field of the prevention and treatment of autoimmune diseases. In this paper, the effects of aerobic exercise on immune system and autoimmune diseases in recent years are reviewed, and the related mechanisms are discussed. It is pointed out that aerobic exercise can improve the homeostasis of immune environment by affecting the number and function of immune cells, inhibit the systemic inflammatory response of the body, and then delay the occurrence and development of autoimmune diseases. 

Key words: aerobic exercise; immunity; autoimmune diseases; inflammation

收稿日期:2019-02-21  录用日期:2019-05-14

通讯作者:王军朋  E-mail:

DOI: 10.13294/j.aps.2019.0062


谢宇, 王军朋. 有氧运动对免疫系统和自身免疫病的影响研究进展[J]. 生理学报 2019; 71 (5): 769-782.

XIE Yu, WANG Jun-Peng. Advance in effect of aerobic exercise on immune system and autoimmune diseases. Acta Physiol Sin 2019; 71 (5): 769-782 (in Chinese with English abstract).