Received 2001-12-10 Accepted 2002-04-12

This work was supported by the National Natural Science Foundation of China (No.30030040) and the National Basic Research Programme of China (No.G1999054000)

*Corresponding author. Tel: +86-29-3374590; Fax: +86-29-3246270: E-mail: sjhu@fmmu.edu.cn

生理学报, Aug. 2002, 54 (4): 329~332

Acta Physiologica Sinica

研究论文

大鼠损伤神经的三种诱发簇放电节律

段玉斌1, 胡三觉1, *, 菅 忠2, 段建红1

第四军医大学 1神经科学研究所、 2物理学教研室, 西安 710032

摘 要: 实验运用单纤维记录技术, 观察了损伤神经起步点自发放电在改变[Ca2+]o和veratridine作用下放电节律的变化。结果表明: 在每一标本上, 记录到的相同背景的自发放电在低与高Ca2+浓度和veratridine的作用下, 转化为三种不同类型的簇放电。结果提示, 神经元放电的节律形式与刺激的性质相关, 不同的节律形式可能携带着不同的神经信息。

关键词: 自发放电; 簇放电; 放电节律; 神经编码

学科分类号: Q424

Three types of induced bursting rhythm in rat injured nerves

DUAN Yu-Bin1, HU San-Jue1,* JIAN Zhong2, DUAN Jian-Hong1

1Institute of Neuroscience and 2Department of Physics, Fourth Military Medical University, Xi'an 710032

Abstract: Firing patterns of injured nerve fibers were recorded using the single-fiber firing recording technique. Under the same background firing pattern, three types of bursting were induced separately by EGTA, veratridine or high [Ca2+]o in the same type of nerve fibers. The results suggest that different firing patterns are related to different stimuli, which means that each firing pattern carries corresponding neural information.

Key words: spontaneous firing; bursting; firing pattern; neural coding