罗非，1966年5月出生于辽宁大连

学历

l         1984.8-1990.8：北京医科大学基础医学专业，本科生，获医学学士学位

l         1990.8-1995.8：北京医科大学生理学系，研究生(提前攻博)，获医学博士学位

工作经历

l         1995.8-1998.7：北京医科大学生理学系，讲师

l         1998.8-2004.6：北京大学基础医学院神经生物学系，副教授

l         1999.12-2000.12：美国北卡罗来那州维克林大学生理药理学系，访问学者

l         2003.1-2003.7：美国北卡罗来那州维克林大学生理药理学系，访问教授

l         2004.6-2005.10：北京大学基础医学院神经生物学系：教授

l         2005.11-至今：中国科学院心理研究所心理健康重点实验室，研究员

主要学术任职

l         《中国疼痛医学杂志》副主编

l         《中华中西医杂志》常务编委

l         北京市疼痛学会理事

l         中华医学会疼痛学分会青年委员

l         中国神经科学学会神经心理学专业委员会委员

l         美国神经科学学会会员

主要学术成就

长期从事痛觉编码与调制机制研究、阿片成瘾及其防治机制研究及深部脑刺激治疗运动系统疾病的研究。已发表研究论文七十余篇。主要成绩包括：

l         痛觉编码研究：首次从神经元群活动的水平证实，内侧和外侧痛觉系统在编码痛觉刺激的过程中存在明确的分工；首次证实痛觉编码系在丘脑-皮层神经网络的参与下完成，在痛觉编码过程中，存在大量的由皮层向丘脑的下行信息流动过程。

l         痛觉调制研究：首次揭示了电针镇痛在神经网络水平的机制，即主要削弱外侧痛觉系统对痛感觉成分的传递并降低丘脑与皮层神经元活动之间的相关性；首次提出丘脑背内侧核可能在电针镇痛中发挥重要作用；首次将中枢功能活动强度与行为学指标进行相互关联的考察，并据此确定了电针所激活中枢脑区中的镇痛相关部位.

l         外周电刺激频率和部位特异性效应研究：首次在单个神经元水平和中枢神经元网络水平研究外周电刺激的频率效应，证实不同频率电刺激可以选择性地兴奋中枢不同的神经元，并导致核团之间不同的信息流动改变；首次利用功能磁共振成像技术证实不同频率、不同部位外周电刺激可激活中枢不同网络。

l         阿片成瘾及其防治机制研究：率先创建吗啡条件性位置偏爱的消退后重建模型作为阿片心瘾戒断后复发模型；首次提出环境应激和药物点燃导致的复吸具有不同的中枢机制；首次证实外周电刺激可抑制吗啡及可卡因诱导的条件性位置偏爱，且该效应具有频率特异性。

Selected Publications

1.         Chang JY, Shi LH, Luo F, Woodward DJ (2006) Deep brain stimulation of the substantia nigra pars reticulata exerts long lasting suppression of amygdala kindled seizures. Brain Res, in press.

2.         Huang J, Chang JY, Woodward DJ, Baccalá LA, Han JS, Luo F* (2006) Dynamic neuronal responses in cortical and thalamic areas during different phases of formalin test in rats. Exp Neurol, in press.

3.         Shi LH, Luo F, Woodward DJ, Chang JY. Basal ganglia neural responses during behaviorally effective deep brain stimulation of the subthalamic nucleus in rats performing a treadmill locomotion test. Synapse. 2006 Mar 6;59(7):445-457 [Epub ahead of print]

4.         Chang JY, Shi LH, Luo F, Woodward DJ (2005) Neural responses in multiple basal ganglia regions following unilateral dopamine depletion in behaving rats performing a treadmill locomotion task. Exp Brain Res, Dec 21;:1-15 [Epub ahead of print].

5.         Yang H, Chang JY, Woodward DJ, Baccalá LA, Han JS, Luo F* (2005) Coding of peripheral electrical stimulation frequency in thalamocortical pathways. Exp Neurol, 196(1):138-152.

6.         Shi LH, Luo F, Woodward DJ, Chang JY (2005) Dose and behavioral context dependent inhibition of movement and basal ganglia neural activity by D-9-THC during spontaneous and treadmill locomotion tasks in rats. Synapse, 55 (1): 1-16.

7.         Ji D, Sui ZY, Ma YY, Luo F, Cui CL, Han JS (2004) NMDA receptor in nucleus accumbens is implicated in morphine withdrawal in rats. Neurochem Res, 29 (11): 2113-2120.

8.         Shi XD, Wang GB, Ma YY, Ren W, Luo F, Cui CL, Han JS (2004) Repeated peripheral electrical stimulations suppress both morphine-induced CPP and reinstatement of extinguished CPP in rats: accelerated expression of PPE and PPD mRNA in NAc implicated. Mol Brain Res, 130 (1-2): 124-133.

9.         Shi LH, Luo F, Woodward DJ, Chang JY (2004) Neural responses in multiple basal ganglia regions during spontaneous and treadmill locomotion tasks in rats. Exp Brain Res, 157 (3):303-314.

10.     Wang JY, Zhang HT, Han JS, Chang JY, Woodward DJ, Luo F* (2004) Differential modulation of nociceptive neural responses in medial and lateral pain pathways by peripheral electrical stimulation: a multichannel recording study. Brain Res, 1014 (1-2): 197-208.

11.     Shi LH, Woodward DJ, Luo F, Anstrom K, Schallert T, Chang JY (2004) High-frequency stimulation of the subthalamic nucleus reverses limb-use asymmetry in rats with unilateral 6-hydroxydopamine lesions. Brain Res, 1013 (1): 98-106.

12.     Sun RQ, Wang HC, Wan Y, Jing Z, Luo F, Han JS, Wang Y (2004) Suppression of neuropathic pain by peripheral electrical stimulation in rats: m-opioid receptor and NMDA receptor implicated. Exp Neurol, 187 (1): 23-29..

13.     Zhang WT, Jin Z, Luo F*, Zhang L, Zeng YW, Han JS* (2004) Evidence from brain imaging with fMRI supporting functional specificity of acupoints in humans. Neurosci Lett, , 354 (1): 50-53.

14.     Wang JY, Luo F*, Chang JY, Woodward DJ, Han JS (2003) Parallel pain processing in freely moving rats revealed by distributed neuron recording. Brain Res, 992 (2): 263-271.

15.     Chang JY, Shi LH, Luo F, Woodward DJ (2003) High frequency stimulation of the subthalamic nucleus improves treadmill locomotion in unilateral 6-hydroxydopamine lesioned rats. Brain Res, 983: 174-184.

16.     Zhang WT, Jin Z, Huang J, Zhang L, Zeng YW, Luo F*, Chen CAN, Han JS (2003) Modulation of cold pain in human brain by electric acupoint stimulation: evidence from fMRI. NeuroReport, 14 (12): 1591-1596.

17.     Zhang WT, Jin Z, Cui GH, Zhang KL, Zhang L, Zeng YW, Luo F*, Chen CAN, Han JS (2003) Relations between brain network activation and analgesic effect induced by low versus high frequency electrical acupoint stimulation in different subjects: a functional magnetic resonance imaging study. Brain Res, 982 (2): 168-178.

18.     Shi XD, Ren W, Wang GB, Luo F, Han JS, Cui CL (2003) Brain opioid-receptors are involved in mediating peripheral electric stimulation-induced inhibition of morphine conditioned place preference in rats. Brain Res, 981: 23-28.

19.     Chang JY, Chen L, Luo F, Shi LH, Woodward DJ (2002) Neuronal responses in the frontal cortico-basal ganglia system during delayed matching-to-sample task: ensemble recording in freely moving rats. Exp Brain Res, 142: 67-80

20.     Wang B, Luo F*, Ge XC, Fu AH, Han JS (2002) Effects of lesions of various brain areas on drug priming or footshock-induced reactivation of extinguished conditioned place preference. Brain Research, 950 (1-2):1-9

21.     Ren YH, Wang B, Luo F*, Cui CL, Zheng JW, Han JS (2002) Peripheral electric stimulation attenuates the expression of cocaine-induced place preference in rats. Brain Research, 957 (1): 129-135.

22.     Wang B, Luo F, Zhang WT, Han JS (2000) Stress or drug priming induces reinstatement of extinguished conditioned place preference. Neuroreport, 2000, 12: 2781-2784.

23.     Han NL, Luo F, Bian ZP, Han JS (2000) Synergistic effect of cholecystokinin octapeptide and angiotensin II in reversal of morphine induced analgesia in rats. Pain, 85: 465-469.

24.     Zhao CS, Sun RQ, Li BS, Wang Y, Luo F, Wang XM, Chang JK, Han JS (2000) Effect of nocistatin in pain modulation. Chin Sci Bull, 45 (8): 716-720.

25.     Wang B, Luo F, Xia YQ, Han JS (2000) Peripheral electric stimulation inhibits morphine-induced place preference in rats. Neuroreport, 11:1017-1020.

26.     Zhao CS, Li BS, Zhao GY, Liu HX, Luo F, Wang Y, Tian JH, Chang JK, Han JS (1999) Nocistatin reverses the effect of orphanin FQ/nociceptin in antagonizing morphine analgesia. Neuroreport, 10 (2): 297-299.