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王中峰,
男,
博士,
1965年1月生,
籍贯河南洛阳.
1990年毕业于中国医科大学,获医学学士学位,
1993年毕业于第三军医大学(生理专业),
获医学硕士学位,
1997年毕业于重庆医科大学(神经药理专业),
获医学博士学位.
1998年6月至2001年2月,中国科学院上海生理研究所博士后.
曾任中国科学院上海生命科学研究院神经生物学重点实验室副研究员.
现为美国西北大学Feinberg
医学院生理系访问学者.
研究兴趣:
突触生理学(突触可塑性).
中国生理学会会员,
Society
for Neuroscience会员.
自2002年起兼任<生理学报>编委.
曾先后获得中国科学院王宽诚博士后工作奖励基金;中国生理学会张锡均基金会优秀论文奖;上海-联合利华研究与发展基金奖学金;明治乳业生命科学奖;Leica神经科学奖;军队科技进步二等奖和上海市科技进步三等奖各一项。
Selected publications:
Wang Z, Kai L, Day M, Ronesi J,
Yin HH, Ding J, Tkatch T, Lovinger D, Surmeier DJ. (2006).
Dopaminergic control of corticostriatal long-term synaptic
depression in medium spiny neurons is mediated by cholinergic
interneurons. Neuron (in press).
Day M, Wang Z, Ding J, An X, Ingham CA, Shering AF, Wokosin D,
Ilijic E, Sun Z, Sampson AR, Mugnaini E, Deutch AY, Sesack SR,
Arbuthnott GW, Surmeier DJ. (2006). Selective elimination of
glutamatergic synapses on striatopallidal neurons in Parkinson's
disease models. Nature Neuroscience 9, 251-259.
Zhang B, Wang ZF, Tang MZ, Shi YL. (2005). Induction of
cytotoxicity and apoptosis in human cancer cell lines by
toosendanin, a triterpenoid derivative extracted from Chinese
traditional medicine. Investigational New Drugs 23, 547-553.
Tang MZ, Wang ZF, Shi YL. (2004). Involvement of cytochrome c
release and caspase activation in toosendanin-induced PC12 cell
apoptosis. Toxicology 201, 31-38.
Li MF, Wu Y, Wang ZF, Shi YL. (2004). Toosendanin, a
triterpenoid derivative, increases Ca2+ current in NG108-15
cells via L-type channels. Neuroscience Research 49: 197-203.
Shi YL, Wang ZF. (2004). Studies on cure of experimental
botulism and antibotulismic effect of toosendanin, a
triterpenoid derivative from Chinese traditional medicine
(review). Acta Pharmacologica Sinica 25, 839-848.
Kai L, Wang ZF, Shi YL, Liu LM, Hu DY. (2004). Opioid receptor
antagonists increase the intracellular free Ca2+ concentration
in arterial smooth muscle cells of rats in hemorrhagic shock.
Acta Pharmacologica Sinica 25, 395-400.
Zhou JY, Wang ZF, Ren XM, Tang MZ, Shi YL. (2003). Antagonism of
botulinum toxin type A-induced cleavage of SNAP-25 in rat
cerebral synaptosome by toosendanin. FEBS Letters 555, 375-379.
Kai L, Wang ZF, Hu DY, Shi YL, Liu LM (2003). Opioid receptor
antagonists modulate Ca2+-activated K+ channels in arterial
smooth muscle cells of rats in hemorrhagic shock. Shock 19:
85-90.
Tang MZ, Wang ZF, Shi YL (2003). Toosendanin induces outgrowth
of neuronal processes and apoptosis in PC12 cells. Neuroscience
Research 45: 223-229.
Wu Y, Wang ZF, Shi YL (2002). Beta-agkistrodotoxin inhibits
large-conductance calcium-activated potassium channels in rat
hippocampal CA1 pyramidal neurons. Brain Research 940: 21-26.
Kai L, Wang ZF, Hu DY, Shi YL, Liu LM (2002). Modulation of Ca2+
channels by opioid receptor antagonists in mesenteric arterial
smooth muscle cells of rats in hemorrhagic shock. Journal of
Cardiovascular Pharmacology 40: 618-624.
Wang ZF, Shi YL (2001). Inhibition of large-conductance
Ca2+-activated K+ channel in hippocampal neurons by toosendanin.
Neuroscience 104: 41-47.
Wang ZF, Shi YL (2001). Toosendanin-induced inhibition of
small-conductance Ca2+-activated K+ channel in hippocampal
neurons. Neuroscience Letters 303: 13-16.
Wang ZF, Shi YL (2001). Modulation of inward rectifier potassium
channel by toosendanin, a presynaptic blocker. Neuroscience
Research 40: 211-215.
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