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Wei-Jin Zang （M.D.;
Ph.D.）
Female, Ph.D.（U.K.）；Postdoc.（U.K.，USA;
Invited Professor (
Japan
,
USA
)
Professor
and vice dean in
School
of
Medicine
,
Xian
Jiaotong
University
Head
in Division of Cardiovascular Physiology and Pharmacology
Address：Division
of Cardiovascular Physiology and Pharmacology；School
of Medicine, Xian Jiaotong University；
P.O. Box
77
#, Xian, P.R.of
China
710061
Tel：029-82655150
or 82655003
Fax：029-82655003
E-mail:
zwj@mail.xjtu.edu.cn
Research
Interests：
My main interests in research are in Cardiovascular Physiology
and Pharmacology. Recently, our research is confined to the
following areas:
1.
Studying
the effects of neurotransmitters and other related factors on
ion channels and calcium signaling transduction in
cardiovascular system using patch clamp technique and confocal
microscope.
2.
Studying
the underlying mechanisms of the ischemic cardiac disease and
diabetic cardiomyopathy.
Selected
publications：
1.
Zang,
W.-J.,
Yu, X.-J., Honjo, H., Kirby, M. S. & Boyett, M. R. (1993).On
the role of G protein activation and phosphorylation in
desensitization to acetylcholine in guinea-pig atrial cells. Journal
of Physiology 464, 649-679
2.
Zang,
W.-J.,
Yu, X.-J. & Boyett, M. R. (1995). Barium block of the
muscarinic potassium current in guinea-pig atrial cells. Pflügers Arch- European J Physiology 430:348-357
3.
Parker.
I.
, Zang. W.-J. &
Wier. W. G. (1996). Ca2+
‘sparks’ involving multiple Ca2+ release
sites along Z lines in rat heart cells. Journal
of Physiology 497.1:31-38
4.
Zang,
W. - J.,
Parker.
I.
, Balke. C. W., Wier. W. G., (1997). Ca2+ Sparks
triggered by L-type Ca2+ currents can involve
multiple sites. Biophysical
Journal 72(2):A342
5.
Shui. Z., Boyett, M. R. & Zang, W.-J. (1997). ATP-dependent desensitization of the muscarinic
K+ channel in rat atrial cells. Journal
of Physiology 505(1):77-93
6.
Zang,
W.-J.,
Morishima, S., Ohara, M., and Okada, Y. (1999) .Cell volume
regulation observed by two-photon laser imaging system.
Japanese Journal of Physiology
49:73
7.
Zang,
W.-J.,
Balke, C.W. & Wier. W.G. (2001). Grader α1-adrenoceptor
activation of arteries involves recruitment of smooth muscle
cells to produce ’all or none’Ca2+ signals. Cell Calcium 29（5）：327-334
8.
Zang,
W.-J.,
Yu Xiaojiang.& Zang Yimin. (2003). Ca2+ sparks
evoked by depolarization of rat heart cells involve multiple
release sites. Acta
Pharmacologica Sinica. 24(6):555-562
9.
Liu Shu-Qin， Zang
W-J*, Zeng-Li Li,
Xiao-Jiang Yu, and Bao-Ping Li.(2004) Effect of Atropine
on Denervated Rabbit Ear’s Blood Vessels. Journal of
Cardiovascular Pharmacology 43(1):99-105
10.
Zang
W-J,
Chen Lina, Yu Xiaojiang, Fang Ping, Lv Jun，Sun
Qiang. （2005）Comparison
of acetylcholine on electric-mechanical characteristics of
guinea-pig atrium and ventricle. Experimental Physiology
90（1）：123-130
11.
Jun Lu, Zang W-J*,
Li-Na Chen, Xiao-Jiang Yu, Chun-Hong Zhang, Bing Jia (2005).
Effects of ischemia-mimetic factors on isolated rat ventricular
myocytes. Experimental Physiology 90（4）：497-505
Key Words:
Neurotransmitters；Acetylcholine；Heart；Vessel；Calcium
signaling；Ion
Channels; ischemic cardiac disease.
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