Changes of inhibitory amino acid in the monkey frontal cortex during a figure recognition guided sequential movement task
Shen Limin, Chen Yuchu
Shanghai Institute of Brain Research,Chinese Academy of Sciences.Shanghai 200031
The levels of #gamma#-aminobutyric acid (GABA) and glycine (Gly) in the micro-dialysate from the monkey frontal cortex were measured by using the techniques of intracerebral microdialysis and high performance liquid chromatography with fluorescent detection while the animal was performing the Figure Recognition Motor Sequence (FRS) task. The probes were sited in the prefrontal cortex (PFC, 46 area), premotor cortex (PM, F7 and F2 areas) and primary motor cortex (MI, F1 area). The results showed that the level of GABA in PFC increased during the FRS task, whereas the level of Gly showed no significant changes.
沈丽敏, 陈郁初. 猕猴在执行图形引导的有序运动过程中额叶皮层抑制性氨基酸变化的初步观察[J]. 生理学报 1999; 51 (6): .
Shen Limin, Chen Yuchu. Changes of inhibitory amino acid in the monkey frontal cortex during a figure recognition guided sequential movement task. Acta Physiol Sin 1999; 51 (6): (in Chinese with English abstract).