郭华, 李菁锦, 吕国蔚
Effects of ketamine on neuronal activity of the spinal dorsal horn in rats with unilateral hindpaw inflammation
Guo Hua, Li Jingjin, Lu Guowei
Department of Neurobiology,Capital University of Medical Sciences.Beijing 100054
A total of 32 units were extracellularly recorded from the spinal dorsal horn of rats. Unitary discharges evoked by stimulation of A and C fiber in ipsilateral lateral and medial plantar nerve were increased after carrageenan injection to be planter area. The evoked responses to both A and C fiber were significantly decreased or even disappeared after administration of ketamine. The windup phenomenon was observed in neurons located deeply in the dorsal horn following carrageenan injection and was significantly suppressed or abolished after ketamine administration.
郭华, 李菁锦, 吕国蔚. 氯胺酮对单足致炎大鼠脊髓背角神经元活动的影响[J]. 生理学报 2000; 52 (4): .
Guo Hua, Li Jingjin, Lu Guowei. Effects of ketamine on neuronal activity of the spinal dorsal horn in rats with unilateral hindpaw inflammation. Acta Physiol Sin 2000; 52 (4): (in Chinese with English abstract).