ISSN 0371-0874, CN 31-1352/Q



刘艺涵, 孔炜*

北京大学医学部生理学与病理生理学系,北京 100191



关键词: 血管钙化; 血管平滑肌细胞; 机制


[The mechanisms of medial vascular calcification .] [Article in Chinese]

LIU Yi-Han, KONG Wei*

Department of Physiology and Pathophysiology, Peking University Health Science Center, Beijing 100191, China


Vascular calcification is an active, invertible and highly regulated pathophysiological process, characterized by the deposition of hydroxyapatite crystal in vascular wall. Vascular calcification is classified into two types based on the sites of calcification: intimal atherosclerotic calcification and Mönckeberg’s medial calcification. Medial vascular calcification is a pathological phenomenon commonly existed in diabetes, chronic kidney failure and aging. The current review summarizes the mechanisms of medial vascular calcification.

Key words: vascular calcification; vascular smooth muscle cells; mechanism

收稿日期:2016-04-05  录用日期:2016-07-08

通讯作者:孔炜  E-mail:


刘艺涵, 孔炜. 血管中膜钙化的机制[J]. 生理学报 2016; 68 (5): 592-610.

LIU Yi-Han, KONG Wei. [The mechanisms of medial vascular calcification .] [Article in Chinese]. Acta Physiol Sin 2016; 68 (5): 592-610 (in Chinese with English abstract).