ISSN 0371-0874, CN 31-1352/Q



王欣, 李安安, 吴飞健

华中师范大学生命科学学院,武汉 430079;湖北第二师范学院化学与生命科学系,武汉 430205;中国科学院武汉物理与数学研究所/ 波谱与原子分子物理国家重点实验室,武汉 430071



关键词: 时程调谐; 时间整合; 中枢听觉系统; 下丘


[Perception and selectivity of sound duration in the central auditory midbrain.] [Ariticle in Chinese]

WANG Xin, LI An-An, WU Fei-Jian

College of Life Science, Central China Normal University, Wuhan 430079, China; Department of Life Sciences and Chemistry, Hubei University of Education, Wuhan 430205, China; Wuhan Institute of Physics and Mathematics, the Chinese Academy of Sciences/State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan 430071, China


Sound duration plays important role in acoustic communication. Information of acoustic signal is mainly encoded in the amplitude and frequency spectrum of different durations. Duration selective neurons exist in the central auditory system including inferior colliculus (IC) of frog, bat, mouse and chinchilla, etc., and they are important in signal recognition and feature detection. Two
generally accepted models, which are “coincidence detector model” and “anti-coincidence detector model”, have been raised to explain the mechanism of neural selective responses to sound durations based on the study of IC neurons in bats. Although they are different in details, they both emphasize the importance of synaptic integration of excitatory and inhibitory inputs, and are able to explain the responses of most duration-selective neurons. However, both of the hypotheses need to be improved since other sound parameters, such as spectral pattern, amplitude and repetition rate, could affect the duration selectivity of the neurons. The dynamic changes of
sound parameters are believed to enable the animal to effectively perform recognition of behavior related acoustic signals. Under free
field sound stimulation, we analyzed the neural responses in the IC and auditory cortex of mouse and bat to sounds with different
duration, frequency and amplitude, using intracellular or extracellular recording techniques. Based on our work and previous studies,
this article reviews the properties of duration selectivity in central auditory system and discusses the mechanisms of duration
selectivity and the effect of other sound parameters on the duration coding of auditory neurons.

Key words: duration tuning; temporal integration; central auditory system; inferior colliculus

收稿日期:2010-02-22  录用日期:2010-06-09

通讯作者:吴飞健  E-mail:


王欣, 李安安, 吴飞健. 中枢听觉系统对声音时程的调谐和识别[J]. 生理学报 2010; 62 (4): 309-316.

WANG Xin, LI An-An, WU Fei-Jian. [Perception and selectivity of sound duration in the central auditory midbrain.] [Ariticle in Chinese] . Acta Physiol Sin 2010; 62 (4): 309-316 (in Chinese with English abstract).