ISSN 0371-0874, CN 31-1352/Q

Current Issue

Application of fiber photometry in neuroscience research

ZHANG Li-Wei1, BI Ai-Ling2,3, , LI Qian1

1Shandong University of Traditional Chinese Medicine Medical College of Optometry and Ophthalmology, Jinan 250014, China;2ffiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250002, China;3Eye Institute of Shandong University of Traditional Chinese Medicine, Shandong Province Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Disease, Key Laboratory of Integrative Medicine for Prevention and Treatment of Ocular Diseases in Colleges and Universities of Shandong Province, Jinan 250002, China


 In recent years, fiber photometry has been widely used in the field of neuroscience as an important technique for recording the activity of neurons in the specific nuclei of freely moving animal. This review summarized the application of single-channel, multi-channel, and multi-color fiber photometry techniques in the neuroscience research of cognition, behavior, psychology and neurological diseases. In addition, it briefly introduced the applications of fiber photometry combined with functional magnetic resonance imaging technology, and fiber photometry combined with probe technology in the neuroscience research.

Key words: fiber photometry; single-channel, multi-channel, multi-color fiber photometry; neuroscience; neurological disease

Received: 2020-07-03  Accepted: 2020-12-10

Corresponding author: BI Hong-Sheng  E-mail:,

Citing This Article:

ZHANG Li-Wei, BI Ai-Ling, LI Qian, BI Hong-Sheng. Application of fiber photometry in neuroscience research. Acta Physiol Sin 2021; 73 (2): 306-314 (in Chinese with English abstract).